Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain)
1_MKTLQ 6_ FFFLF 11_ CCWKA 16_ ICCNS 21_ CELTN 26_ ITIAI 31_ EKEEC 36_ RFCIS 41_ INTTW 46_ CAGYC 51_ YTRDL 56_ VYKDP 61_ ARPKI 66_ QKTCT 71_ FKELV 76_ YETVR 81_ VPGCA 86_ HHADS 91_ LYTYP 96_ VATQC 101_ HCGKC 106_ DSDST 111_ DCTVR 116_ GLGPS 121_YCSFG
1: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:24692546, PubMed:2494176). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432)