Gene name: PTH

Uniprot entry:

P01270

Protein names:

Parathyroid hormone (PTH) (Parathormone) (Parathyrin)

Protein sequence:

1_MIPAK 6_ DMAKV 11_ MIVML 16_ AICFL 21_ TKSDG 26_ KSVKK 31_ RSVSE 36_ IQLMH 41_ NLGKH 46_ LNSME 51_ RVEWL 56_ RKKLQ 61_ DVHNF 66_ VALGA 71_ PLAPR 76_ DAGSQ 81_ RPRKK 86_ EDNVL 91_ VESHE 96_ KSLGE 101_ ADKAD 106_VNVLT

Protein annotations

Protein functions:

1: Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion (PubMed:11604398, PubMed:35932760). Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling (PubMed:18375760, PubMed:35932760). Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells (PubMed:21076856)