Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)
1_MTPPE 6_ RLFLP 11_ RVCGT 16_ TLHLL 21_ LLGLL 26_ LVLLP 31_ GAQGL 36_ PGVGL 41_ TPSAA 46_ QTARQ 51_ HPKMH 56_ LAHST 61_ LKPAA 66_ HLIGD 71_ PSKQN 76_ SLLWR 81_ ANTDR 86_ AFLQD 91_ GFSLS 96_ NNSLL 101_ VPTSG 106_ IYFVY 111_ SQVVF 116_ SGKAY 121_ SPKAT 126_ SSPLY 131_ LAHEV 136_ QLFSS 141_ QYPFH 146_ VPLLS 151_ SQKMV 156_ YPGLQ 161_ EPWLH 166_ SMYHG 171_ AAFQL 176_ TQGDQ 181_ LSTHT 186_ DGIPH 191_ LVLSP 196_STVFF
1: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR (PubMed:24248355). Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo