Gene name: JCHAIN

Uniprot entry:

P01591

Protein names:

Immunoglobulin J chain (Joining chain of multimeric IgA and IgM)

Protein sequence:

1_MKNHL 6_ LFWGV 11_ LAVFI 16_ KAVHV 21_ KAQED 26_ ERIVL 31_ VDNKC 36_ KCARI 41_ TSRII 46_ RSSED 51_ PNEDI 56_ VERNI 61_ RIIVP 66_ LNNRE 71_ NISDP 76_ TSPLR 81_ TRFVY 86_ HLSDL 91_ CKKCD 96_ PTEVE 101_ LDNQI 106_ VTATQ 111_ SNICD 116_ EDSAT 121_ ETCYT 126_ YDRNK 131_ CYTAV 136_ VPLVY 141_ GGETK 146_ MVETA 151_LTPDA

Protein annotations

Protein functions:

1: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component