Troponin C, skeletal muscle
1_MTDQQ 6_ AEARS 11_ YLSEE 16_ MIAEF 21_ KAAFD 26_ MFDAD 31_ GGGDI 36_ SVKEL 41_ GTVMR 46_ MLGQT 51_ PTKEE 56_ LDAII 61_ EEVDE 66_ DGSGT 71_ IDFEE 76_ FLVMM 81_ VRQMK 86_ EDAKG 91_ KSEEE 96_ LAECF 101_ RIFDR 106_ NADGY 111_ IDPEE 116_ LAEIF 121_ RASGE 126_ HVTDE 131_ EIESL 136_ MKDGD 141_ KNNDG 146_ RIDFD 151_EFLKM
1: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments