Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2) [Cleaved into: Proapolipoprotein C-II (ProapoC-II)]
1_MGTRL 6_ LPALF 11_ LVLLV 16_ LGFEV 21_ QGTQQ 26_ PQQDE 31_ MPSPT 36_ FLTQV 41_ KESLS 46_ SYWES 51_ AKTAA 56_ QNLYE 61_ KTYLP 66_ AVDEK 71_ LRDLY 76_ SKSTA 81_ AMSTY 86_ TGIFT 91_ DQVLS 96_VLKGE
1: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL