Gene name: F11

Uniprot entry:

P03951

Protein names:

Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]

Protein sequence:

1_MIFLY 6_ QVVHF 11_ ILFTS 16_ VSGEC 21_ VTQLL 26_ KDTCF 31_ EGGDI 36_ TTVFT 41_ PSAKY 46_ CQVVC 51_ TYHPR 56_ CLLFT 61_ FTAES 66_ PSEDP 71_ TRWFT 76_ CVLKD 81_ SVTET 86_ LPRVN 91_ RTAAI 96_ SGYSF 101_ KQCSH 106_ QISAC 111_ NKDIY 116_ VDLDM 121_ KGINY 126_ NSSVA 131_ KSAQE 136_ CQERC 141_ TDDVH 146_ CHFFT 151_ YATRQ 156_ FPSLE 161_ HRNIC 166_ LLKHT 171_ QTGTP 176_ TRITK 181_ LDKVV 186_ SGFSL 191_ KSCAL 196_ SNLAC 201_ IRDIF 206_ PNTVF 211_ ADSNI 216_ DSVMA 221_ PDAFV 226_ CGRIC 231_ THHPG 236_ CLFFT 241_ FFSQE 246_ WPKES 251_ QRNLC 256_ LLKTS 261_ ESGLP 266_ STRIK 271_ KSKAL 276_ SGFSL 281_ QSCRH 286_ SIPVF 291_ CHSSF 296_ YHDTD 301_ FLGEE 306_ LDIVA 311_ AKSHE 316_ ACQKL 321_ CTNAV 326_ RCQFF 331_ TYTPA 336_ QASCN 341_ EGKGK 346_ CYLKL 351_ SSNGS 356_ PTKIL 361_ HGRGG 366_ ISGYT 371_ LRLCK 376_ MDNEC 381_ TTKIK 386_ PRIVG 391_ GTASV 396_ RGEWP 401_ WQVTL 406_ HTTSP 411_ TQRHL 416_ CGGSI 421_ IGNQW 426_ ILTAA 431_ HCFYG 436_ VESPK 441_ ILRVY 446_ SGILN 451_ QSEIK 456_ EDTSF 461_ FGVQE 466_ IIIHD 471_ QYKMA 476_ ESGYD 481_ IALLK 486_ LETTV 491_ NYTDS 496_ QRPIC 501_ LPSKG 506_ DRNVI 511_ YTDCW 516_ VTGWG 521_ YRKLR 526_ DKIQN 531_ TLQKA 536_ KIPLV 541_ TNEEC 546_ QKRYR 551_ GHKIT 556_ HKMIC 561_ AGYRE 566_ GGKDA 571_ CKGDS 576_ GGPLS 581_ CKHNE 586_ VWHLV 591_ GITSW 596_ GEGCA 601_ QRERP 606_ GVYTN 611_ VVEYV 616_DWILE

Protein annotations

Protein functions:

1: Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX