Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B]
1_MAPLR 6_ PLLIL 11_ ALLAW 16_ VALAD 21_ QESCK 26_ GRCTE 31_ GFNVD 36_ KKCQC 41_ DELCS 46_ YYQSC 51_ CTDYT 56_ AECKP 61_ QVTRG 66_ DVFTM 71_ PEDEY 76_ TVYDD 81_ GEEKN 86_ NATVH 91_ EQVGG 96_ PSLTS 101_ DLQAQ 106_ SKGNP 111_ EQTPV 116_ LKPEE 121_ EAPAP 126_ EVGAS 131_ KPEGI 136_ DSRPE 141_ TLHPG 146_ RPQPP 151_ AEEEL 156_ CSGKP 161_ FDAFT 166_ DLKNG 171_ SLFAF 176_ RGQYC 181_ YELDE 186_ KAVRP 191_ GYPKL 196_ IRDVW 201_ GIEGP 206_ IDAAF 211_ TRINC 216_ QGKTY 221_ LFKGS 226_ QYWRF 231_ EDGVL 236_ DPDYP 241_ RNISD 246_ GFDGI 251_ PDNVD 256_ AALAL 261_ PAHSY 266_ SGRER 271_ VYFFK 276_ GKQYW 281_ EYQFQ 286_ HQPSQ 291_ EECEG 296_ SSLSA 301_ VFEHF 306_ AMMQR 311_ DSWED 316_ IFELL 321_ FWGRT 326_ SAGTR 331_ QPQFI 336_ SRDWH 341_ GVPGQ 346_ VDAAM 351_ AGRIY 356_ ISGMA 361_ PRPSL 366_ AKKQR 371_ FRHRN 376_ RKGYR 381_ SQRGH 386_ SRGRN 391_ QNSRR 396_ PSRAT 401_ WLSLF 406_ SSEES 411_ NLGAN 416_ NYDDY 421_ RMDWL 426_ VPATC 431_ EPIQS 436_ VFFFS 441_ GDKYY 446_ RVNLR 451_ TRRVD 456_ TVDPP 461_ YPRSI 466_ AQYWL 471_GCPAP
1: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway
2: Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity