Proto-oncogene Mas
1_MDGSN 6_ VTSFV 11_ VEEPT 16_ NISTG 21_ RNASV 26_ GNAHR 31_ QIPIV 36_ HWVIM 41_ SISPV 46_ GFVEN 51_ GILLW 56_ FLCFR 61_ MRRNP 66_ FTVYI 71_ THLSI 76_ ADISL 81_ LFCIF 86_ ILSID 91_ YALDY 96_ ELSSG 101_ HYYTI 106_ VTLSV 111_ TFLFG 116_ YNTGL 121_ YLLTA 126_ ISVER 131_ CLSVL 136_ YPIWY 141_ RCHRP 146_ KYQSA 151_ LVCAL 156_ LWALS 161_ CLVTT 166_ MEYVM 171_ CIDRE 176_ EESHS 181_ RNDCR 186_ AVIIF 191_ IAILS 196_ FLVFT 201_ PLMLV 206_ SSTIL 211_ VVKIR 216_ KNTWA 221_ SHSSK 226_ LYIVI 231_ MVTII 236_ IFLIF 241_ AMPMR 246_ LLYLL 251_ YYEYW 256_ STFGN 261_ LHHIS 266_ LLFST 271_ INSSA 276_ NPFIY 281_ FFVGS 286_ SKKKR 291_ FKESL 296_ KVVLT 301_ RAFKD 306_ EMQPR 311_ RQKDN 316_CNTVT
1: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1