von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
1_MIPAR 6_ FAGVL 11_ LALAL 16_ ILPGT 21_ LCAEG 26_ TRGRS 31_ STARC 36_ SLFGS 41_ DFVNT 46_ FDGSM 51_ YSFAG 56_ YCSYL 61_ LAGGC 66_ QKRSF 71_ SIIGD 76_ FQNGK 81_ RVSLS 86_ VYLGE 91_ FFDIH 96_ LFVNG 101_ TVTQG 106_ DQRVS 111_ MPYAS 116_ KGLYL 121_ ETEAG 126_ YYKLS 131_ GEAYG 136_ FVARI 141_ DGSGN 146_ FQVLL 151_ SDRYF 156_ NKTCG 161_ LCGNF 166_ NIFAE 171_ DDFMT 176_ QEGTL 181_ TSDPY 186_ DFANS 191_ WALSS 196_ GEQWC 201_ ERASP 206_ PSSSC 211_ NISSG 216_ EMQKG 221_ LWEQC 226_ QLLKS 231_ TSVFA 236_ RCHPL 241_ VDPEP 246_ FVALC 251_ EKTLC 256_ ECAGG 261_ LECAC 266_ PALLE 271_ YARTC 276_ AQEGM 281_ VLYGW 286_ TDHSA 291_ CSPVC 296_ PAGME 301_ YRQCV 306_ SPCAR 311_ TCQSL 316_ HINEM 321_ CQERC 326_ VDGCS 331_ CPEGQ 336_ LLDEG 341_ LCVES 346_ TECPC 351_ VHSGK 356_ RYPPG 361_ TSLSR 366_ DCNTC 371_ ICRNS 376_ QWICS 381_ NEECP 386_ GECLV 391_ TGQSH 396_ FKSFD 401_ NRYFT 406_ FSGIC 411_ QYLLA 416_ RDCQD 421_ HSFSI 426_ VIETV 431_ QCADD 436_ RDAVC 441_ TRSVT 446_ VRLPG 451_ LHNSL 456_ VKLKH 461_ GAGVA 466_ MDGQD 471_ VQLPL 476_ LKGDL 481_ RIQHT 486_ VTASV 491_ RLSYG 496_ EDLQM 501_ DWDGR 506_ GRLLV 511_ KLSPV 516_ YAGKT 521_ CGLCG 526_ NYNGN 531_ QGDDF 536_ LTPSG 541_ LAEPR 546_ VEDFG 551_ NAWKL 556_ HGDCQ 561_ DLQKQ 566_ HSDPC 571_ ALNPR 576_ MTRFS 581_ EEACA 586_ VLTSP 591_ TFEAC 596_ HRAVS 601_ PLPYL 606_ RNCRY 611_ DVCSC 616_ SDGRE 621_ CLCGA 626_ LASYA 631_ AACAG 636_ RGVRV 641_ AWREP 646_ GRCEL 651_ NCPKG 656_ QVYLQ 661_ CGTPC 666_ NLTCR 671_ SLSYP 676_ DEECN 681_ EACLE 686_ GCFCP 691_ PGLYM 696_ DERGD 701_ CVPKA 706_ QCPCY 711_ YDGEI 716_ FQPED 721_ IFSDH 726_ HTMCY 731_ CEDGF 736_ MHCTM 741_ SGVPG 746_ SLLPD 751_ AVLSS 756_ PLSHR 761_ SKRSL 766_ SCRPP 771_ MVKLV 776_ CPADN 781_ LRAEG 786_ LECTK 791_ TCQNY 796_ DLECM 801_ SMGCV 806_ SGCLC 811_ PPGMV 816_ RHENR 821_ CVALE 826_ RCPCF 831_ HQGKE 836_ YAPGE 841_ TVKIG 846_ CNTCV 851_ CQDRK 856_ WNCTD 861_ HVCDA 866_ TCSTI 871_ GMAHY 876_ LTFDG 881_ LKYLF 886_ PGECQ 891_ YVLVQ 896_ DYCGS 901_ NPGTF 906_ RILVG 911_ NKGCS 916_ HPSVK 921_ CKKRV 926_ TILVE 931_ GGEIE 936_ LFDGE 941_ VNVKR 946_ PMKDE 951_ THFEV 956_ VESGR 961_ YIILL 966_ LGKAL 971_ SVVWD 976_ RHLSI 981_ SVVLK 986_ QTYQE 991_ KVCGL 996_ CGNFD 1001_ GIQNN 1006_ DLTSS 1011_ NLQVE 1016_ EDPVD 1021_ FGNSW 1026_ KVSSQ 1031_ CADTR 1036_ KVPLD 1041_ SSPAT 1046_ CHNNI 1051_ MKQTM 1056_ VDSSC 1061_ RILTS 1066_ DVFQD 1071_ CNKLV 1076_ DPEPY 1081_ LDVCI 1086_ YDTCS 1091_ CESIG 1096_ DCACF 1101_ CDTIA 1106_ AYAHV 1111_ CAQHG 1116_ KVVTW 1121_ RTATL 1126_ CPQSC 1131_ EERNL 1136_ RENGY 1141_ ECEWR 1146_ YNSCA 1151_ PACQV 1156_ TCQHP 1161_ EPLAC 1166_ PVQCV 1171_ EGCHA 1176_ HCPPG 1181_ KILDE 1186_ LLQTC 1191_ VDPED 1196_ CPVCE 1201_ VAGRR 1206_ FASGK 1211_ KVTLN 1216_ PSDPE 1221_ HCQIC 1226_ HCDVV 1231_ NLTCE 1236_ ACQEP 1241_ GGLVV 1246_ PPTDA 1251_ PVSPT 1256_ TLYVE 1261_ DISEP 1266_ PLHDF 1271_ YCSRL 1276_ LDLVF 1281_ LLDGS 1286_ SRLSE 1291_ AEFEV 1296_ LKAFV 1301_ VDMME 1306_ RLRIS 1311_ QKWVR 1316_ VAVVE 1321_ YHDGS 1326_ HAYIG 1331_ LKDRK 1336_ RPSEL 1341_ RRIAS 1346_ QVKYA 1351_ GSQVA 1356_ STSEV 1361_ LKYTL 1366_ FQIFS 1371_ KIDRP 1376_ EASRI 1381_ TLLLM 1386_ ASQEP 1391_ QRMSR 1396_ NFVRY 1401_ VQGLK 1406_ KKKVI 1411_ VIPVG 1416_ IGPHA 1421_ NLKQI 1426_ RLIEK 1431_ QAPEN 1436_ KAFVL 1441_ SSVDE 1446_ LEQQR 1451_ DEIVS 1456_ YLCDL 1461_ APEAP 1466_ PPTLP 1471_ PDMAQ 1476_ VTVGP 1481_ GLLGV 1486_ STLGP 1491_ KRNSM 1496_ VLDVA 1501_ FVLEG 1506_ SDKIG 1511_ EADFN 1516_ RSKEF 1521_ MEEVI 1526_ QRMDV 1531_ GQDSI 1536_ HVTVL 1541_ QYSYM 1546_ VTVEY 1551_ PFSEA 1556_ QSKGD 1561_ ILQRV 1566_ REIRY 1571_ QGGNR 1576_ TNTGL 1581_ ALRYL 1586_ SDHSF 1591_ LVSQG 1596_ DREQA 1601_ PNLVY 1606_ MVTGN 1611_ PASDE 1616_ IKRLP 1621_ GDIQV 1626_ VPIGV 1631_ GPNAN 1636_ VQELE 1641_ RIGWP 1646_ NAPIL 1651_ IQDFE 1656_ TLPRE 1661_ APDLV 1666_ LQRCC 1671_ SGEGL 1676_ QIPTL 1681_ SPAPD 1686_ CSQPL 1691_ DVILL 1696_ LDGSS 1701_ SFPAS 1706_ YFDEM 1711_ KSFAK 1716_ AFISK 1721_ ANIGP 1726_ RLTQV 1731_ SVLQY 1736_ GSITT 1741_ IDVPW 1746_ NVVPE 1751_ KAHLL 1756_ SLVDV 1761_ MQREG 1766_ GPSQI 1771_ GDALG 1776_ FAVRY 1781_ LTSEM 1786_ HGARP 1791_ GASKA 1796_ VVILV 1801_ TDVSV 1806_ DSVDA 1811_ AADAA 1816_ RSNRV 1821_ TVFPI 1826_ GIGDR 1831_ YDAAQ 1836_ LRILA 1841_ GPAGD 1846_ SNVVK 1851_ LQRIE 1856_ DLPTM 1861_ VTLGN 1866_ SFLHK 1871_ LCSGF 1876_ VRICM 1881_ DEDGN 1886_ EKRPG 1891_ DVWTL 1896_ PDQCH 1901_ TVTCQ 1906_ PDGQT 1911_ LLKSH 1916_ RVNCD 1921_ RGLRP 1926_ SCPNS 1931_ QSPVK 1936_ VEETC 1941_ GCRWT 1946_ CPCVC 1951_ TGSST 1956_ RHIVT 1961_ FDGQN 1966_ FKLTG 1971_ SCSYV 1976_ LFQNK 1981_ EQDLE 1986_ VILHN 1991_ GACSP 1996_ GARQG 2001_ CMKSI 2006_ EVKHS 2011_ ALSVE 2016_ LHSDM 2021_ EVTVN 2026_ GRLVS 2031_ VPYVG 2036_ GNMEV 2041_ NVYGA 2046_ IMHEV 2051_ RFNHL 2056_ GHIFT 2061_ FTPQN 2066_ NEFQL 2071_ QLSPK 2076_ TFASK 2081_ TYGLC 2086_ GICDE 2091_ NGAND 2096_ FMLRD 2101_ GTVTT 2106_ DWKTL 2111_ VQEWT 2116_ VQRPG 2121_ QTCQP 2126_ ILEEQ 2131_ CLVPD 2136_ SSHCQ 2141_ VLLLP 2146_ LFAEC 2151_ HKVLA 2156_ PATFY 2161_ AICQQ 2166_ DSCHQ 2171_ EQVCE 2176_ VIASY 2181_ AHLCR 2186_ TNGVC 2191_ VDWRT 2196_ PDFCA 2201_ MSCPP 2206_ SLVYN 2211_ HCEHG 2216_ CPRHC 2221_ DGNVS 2226_ SCGDH 2231_ PSEGC 2236_ FCPPD 2241_ KVMLE 2246_ GSCVP 2251_ EEACT 2256_ QCIGE 2261_ DGVQH 2266_ QFLEA 2271_ WVPDH 2276_ QPCQI 2281_ CTCLS 2286_ GRKVN 2291_ CTTQP 2296_ CPTAK 2301_ APTCG 2306_ LCEVA 2311_ RLRQN 2316_ ADQCC 2321_ PEYEC 2326_ VCDPV 2331_ SCDLP 2336_ PVPHC 2341_ ERGLQ 2346_ PTLTN 2351_ PGECR 2356_ PNFTC 2361_ ACRKE 2366_ ECKRV 2371_ SPPSC 2376_ PPHRL 2381_ PTLRK 2386_ TQCCD 2391_ EYECA 2396_ CNCVN 2401_ STVSC 2406_ PLGYL 2411_ ASTAT 2416_ NDCGC 2421_ TTTTC 2426_ LPDKV 2431_ CVHRS 2436_ TIYPV 2441_ GQFWE 2446_ EGCDV 2451_ CTCTD 2456_ MEDAV 2461_ MGLRV 2466_ AQCSQ 2471_ KPCED 2476_ SCRSG 2481_ FTYVL 2486_ HEGEC 2491_ CGRCL 2496_ PSACE 2501_ VVTGS 2506_ PRGDS 2511_ QSSWK 2516_ SVGSQ 2521_ WASPE 2526_ NPCLI 2531_ NECVR 2536_ VKEEV 2541_ FIQQR 2546_ NVSCP 2551_ QLEVP 2556_ VCPSG 2561_ FQLSC 2566_ KTSAC 2571_ CPSCR 2576_ CERME 2581_ ACMLN 2586_ GTVIG 2591_ PGKTV 2596_ MIDVC 2601_ TTCRC 2606_ MVQVG 2611_ VISGF 2616_ KLECR 2621_ KTTCN 2626_ PCPLG 2631_ YKEEN 2636_ NTGEC 2641_ CGRCL 2646_ PTACT 2651_ IQLRG 2656_ GQIMT 2661_ LKRDE 2666_ TLQDG 2671_ CDTHF 2676_ CKVNE 2681_ RGEYF 2686_ WEKRV 2691_ TGCPP 2696_ FDEHK 2701_ CLAEG 2706_ GKIMK 2711_ IPGTC 2716_ CDTCE 2721_ EPECN 2726_ DITAR 2731_ LQYVK 2736_ VGSCK 2741_ SEVEV 2746_ DIHYC 2751_ QGKCA 2756_ SKAMY 2761_ SIDIN 2766_ DVQDQ 2771_ CSCCS 2776_ PTRTE 2781_ PMQVA 2786_ LHCTN 2791_ GSVVY 2796_ HEVLN 2801_ AMECK 2806_CSPRK
1: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma