Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein]
1_MKPNI 6_ IFVLS 11_ LLLIL 16_ EKQAA 21_ VMGQK 26_ GGSKG 31_ RLPSE 36_ FSQFP 41_ HGQKG 46_ QHYSG 51_ QKGKQ 56_ QTESK 61_ GSFSI 66_ QYTYH 71_ VDAND 76_ HDQSR 81_ KSQQY 86_ DLNAL 91_ HKTTK 96_ SQRHL 101_ GGSQQ 106_ LLHNK 111_ QEGRD 116_ HDKSK 121_ GHFHR 126_ VVIHH 131_ KGGKA 136_ HRGTQ 141_ NPSQD 146_ QGNSP 151_ SGKGI 156_ SSQYS 161_ NTEER 166_ LWVHG 171_ LSKEQ 176_ TSVSG 181_ AQKGR 186_ KQGGS 191_ QSSYV 196_ LQTEE 201_ LVANK 206_ QQRET 211_ KNSHQ 216_ NKGHY 221_ QNVVE 226_ VREEH 231_ SSKVQ 236_ TSLCP 241_ AHQDK 246_ LQHGS 251_ KDIFS 256_ TQDEL 261_ LVYNK 266_ NQHQT 271_ KNLNQ 276_ DQQHG 281_ RKANK 286_ ISYQS 291_ SSTEE 296_ RRLHY 301_ GENGV 306_ QKDVS 311_ QSSIY 316_ SQTEE 321_ KAQGK 326_ SQKQI 331_ TIPSQ 336_ EQEHS 341_ QKANK 346_ ISYQS 351_ SSTEE 356_ RRLHY 361_ GENGV 366_ QKDVS 371_ QRSIY 376_ SQTEK 381_ LVAGK 386_ SQIQA 391_ PNPKQ 396_ EPWHG 401_ ENAKG 406_ ESGQS 411_ TNREQ 416_ DLLSH 421_ EQKGR 426_ HQHGS 431_ HGGLD 436_ IVIIE 441_ QEDDS 446_ DRHLA 451_ QHLNN 456_DRNPL
1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA
2: Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone