Gene name: HSPB1

Uniprot entry:

P04792

Protein names:

Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)

Protein sequence:

1_MTERR 6_ VPFSL 11_ LRGPS 16_ WDPFR 21_ DWYPH 26_ SRLFD 31_ QAFGL 36_ PRLPE 41_ EWSQW 46_ LGGSS 51_ WPGYV 56_ RPLPP 61_ AAIES 66_ PAVAA 71_ PAYSR 76_ ALSRQ 81_ LSSGV 86_ SEIRH 91_ TADRW 96_ RVSLD 101_ VNHFA 106_ PDELT 111_ VKTKD 116_ GVVEI 121_ TGKHE 126_ ERQDE 131_ HGYIS 136_ RCFTR 141_ KYTLP 146_ PGVDP 151_ TQVSS 156_ SLSPE 161_ GTLTV 166_ EAPMP 171_ KLATQ 176_ SNEIT 181_ IPVTF 186_ ESRAQ 191_ LGGPE 196_AAKSD

Protein annotations

Protein functions:

1: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742)