Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1)
1_MEAPA 6_ AGLFL 11_ LLLLG 16_ TWAPA 21_ PGSAS 26_ SEAPP 31_ LINED 36_ VKRTV 41_ DLSSH 46_ LAKVT 51_ AEVVL 56_ AHLGG 61_ GSTSR 66_ ATSFL 71_ LALEP 76_ ELEAR 81_ LAHLG 86_ VQVKG 91_ EDEEE 96_ NNLEV 101_ RETKI 106_ KGKSG 111_ RFFTV 116_ KLPVA 121_ LDPGA 126_ KISVI 131_ VETVY 136_ THVLH 141_ PYPTQ 146_ ITQSE 151_ KQFVV 156_ FEGNH 161_ YFYSP 166_ YPTKT 171_ QTMRV 176_ KLASR 181_ NVESY 186_ TKLGN 191_ PTRSE 196_ DLLDY 201_ GPFRD 206_ VPAYS 211_ QDTFK 216_ VHYEN 221_ NSPFL 226_ TITSM 231_ TRVIE 236_ VSHWG 241_ NIAVE 246_ ENVDL 251_ KHTGA 256_ VLKGP 261_ FSRYD 266_ YQRQP 271_ DSGIS 276_ SIRSF 281_ KTILP 286_ AAAQD 291_ VYYRD 296_ EIGNV 301_ STSHL 306_ LILDD 311_ SVEME 316_ IRPRF 321_ PLFGG 326_ WKTHY 331_ IVGYN 336_ LPSYE 341_ YLYNL 346_ GDQYA 351_ LKMRF 356_ VDHVF 361_ DEQVI 366_ DSLTV 371_ KIILP 376_ EGAKN 381_ IEIDS 386_ PYEIS 391_ RAPDE 396_ LHYTY 401_ LDTFG 406_ RPVIV 411_ AYKKN 416_ LVEQH 421_ IQDIV 426_ VHYTF 431_ NKVLM 436_ LQEPL 441_ LVVAA 446_ FYILF 451_ FTVII 456_ YVRLD 461_ FSITK 466_ DPAAE 471_ ARMKV 476_ ACITE 481_ QVLTL 486_ VNKRI 491_ GLYRH 496_ FDETV 501_ NRYKQ 506_ SRDIS 511_ TLNSG 516_ KKSLE 521_ TEHKA 526_ LTSEI 531_ ALLQS 536_ RLKTE 541_ GSDLC 546_ DRVSE 551_ MQKLD 556_ AQVKE 561_ LVLKS 566_ AVEAE 571_ RLVAG 576_ KLKKD 581_ TYIEN 586_ EKLIS 591_ GKRQE 596_ LVTKI 601_DHILD
1: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity)