Gene name: HMGN1

Uniprot entry:

P05114

Protein names:

Non-histone chromosomal protein HMG-14 (High mobility group nucleosome-binding domain-containing protein 1)

Protein sequence:

1_MPKRK 6_ VSSAE 11_ GAAKE 16_ EPKRR 21_ SARLS 26_ AKPPA 31_ KVEAK 36_ PKKAA 41_ AKDKS 46_ SDKKV 51_ QTKGK 56_ RGAKG 61_ KQAEV 66_ ANQET 71_ KEDLP 76_ AENGE 81_ TKTEE 86_ SPASD 91_EAGEK

Protein annotations

Protein functions:

1: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity)