Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
1_MTELK 6_ AKGPR 11_ APHVA 16_ GGPPS 21_ PEVGS 26_ PLLCR 31_ PAAGP 36_ FPGSQ 41_ TSDTL 46_ PEVSA 51_ IPISL 56_ DGLLF 61_ PRPCQ 66_ GQDPS 71_ DEKTQ 76_ DQQSL 81_ SDVEG 86_ AYSRA 91_ EATRG 96_ AGGSS 101_ SSPPE 106_ KDSGL 111_ LDSVL 116_ DTLLA 121_ PSGPG 126_ QSQPS 131_ PPACE 136_ VTSSW 141_ CLFGP 146_ ELPED 151_ PPAAP 156_ ATQRV 161_ LSPLM 166_ SRSGC 171_ KVGDS 176_ SGTAA 181_ AHKVL 186_ PRGLS 191_ PARQL 196_ LLPAS 201_ ESPHW 206_ SGAPV 211_ KPSPQ 216_ AAAVE 221_ VEEED 226_ GSESE 231_ ESAGP 236_ LLKGK 241_ PRALG 246_ GAAAG 251_ GGAAA 256_ VPPGA 261_ AAGGV 266_ ALVPK 271_ EDSRF 276_ SAPRV 281_ ALVEQ 286_ DAPMA 291_ PGRSP 296_ LATTV 301_ MDFIH 306_ VPILP 311_ LNHAL 316_ LAART 321_ RQLLE 326_ DESYD 331_ GGAGA 336_ ASAFA 341_ PPRSS 346_ PCASS 351_ TPVAV 356_ GDFPD 361_ CAYPP 366_ DAEPK 371_ DDAYP 376_ LYSDF 381_ QPPAL 386_ KIKEE 391_ EEGAE 396_ ASARS 401_ PRSYL 406_ VAGAN 411_ PAAFP 416_ DFPLG 421_ PPPPL 426_ PPRAT 431_ PSRPG 436_ EAAVT 441_ AAPAS 446_ ASVSS 451_ ASSSG 456_ STLEC 461_ ILYKA 466_ EGAPP 471_ QQGPF 476_ APPPC 481_ KAPGA 486_ SGCLL 491_ PRDGL 496_ PSTSA 501_ SAAAA 506_ GAAPA 511_ LYPAL 516_ GLNGL 521_ PQLGY 526_ QAAVL 531_ KEGLP 536_ QVYPP 541_ YLNYL 546_ RPDSE 551_ ASQSP 556_ QYSFE 561_ SLPQK 566_ ICLIC 571_ GDEAS 576_ GCHYG 581_ VLTCG 586_ SCKVF 591_ FKRAM 596_ EGQHN 601_ YLCAG 606_ RNDCI 611_ VDKIR 616_ RKNCP 621_ ACRLR 626_ KCCQA 631_ GMVLG 636_ GRKFK 641_ KFNKV 646_ RVVRA 651_ LDAVA 656_ LPQPV 661_ GVPNE 666_ SQALS 671_ QRFTF 676_ SPGQD 681_ IQLIP 686_ PLINL 691_ LMSIE 696_ PDVIY 701_ AGHDN 706_ TKPDT 711_ SSSLL 716_ TSLNQ 721_ LGERQ 726_ LLSVV 731_ KWSKS 736_ LPGFR 741_ NLHID 746_ DQITL 751_ IQYSW 756_ MSLMV 761_ FGLGW 766_ RSYKH 771_ VSGQM 776_ LYFAP 781_ DLILN 786_ EQRMK 791_ ESSFY 796_ SLCLT 801_ MWQIP 806_ QEFVK 811_ LQVSQ 816_ EEFLC 821_ MKVLL 826_ LLNTI 831_ PLEGL 836_ RSQTQ 841_ FEEMR 846_ SSYIR 851_ ELIKA 856_ IGLRQ 861_ KGVVS 866_ SSQRF 871_ YQLTK 876_ LLDNL 881_ HDLVK 886_ QLHLY 891_ CLNTF 896_ IQSRA 901_ LSVEF 906_ PEMMS 911_ EVIAA 916_ QLPKI 921_ LAGMV 926_KPLLF
1: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor
2: Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Transrepressional activity may involve recruitment of corepressor NCOR2
3: Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation
4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone