Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
1_MESPS 6_ APPHR 11_ WCIPW 16_ QRLLL 21_ TASLL 26_ TFWNP 31_ PTTAK 36_ LTIES 41_ TPFNV 46_ AEGKE 51_ VLLLV 56_ HNLPQ 61_ HLFGY 66_ SWYKG 71_ ERVDG 76_ NRQII 81_ GYVIG 86_ TQQAT 91_ PGPAY 96_ SGREI 101_ IYPNA 106_ SLLIQ 111_ NIIQN 116_ DTGFY 121_ TLHVI 126_ KSDLV 131_ NEEAT 136_ GQFRV 141_ YPELP 146_ KPSIS 151_ SNNSK 156_ PVEDK 161_ DAVAF 166_ TCEPE 171_ TQDAT 176_ YLWWV 181_ NNQSL 186_ PVSPR 191_ LQLSN 196_ GNRTL 201_ TLFNV 206_ TRNDT 211_ ASYKC 216_ ETQNP 221_ VSARR 226_ SDSVI 231_ LNVLY 236_ GPDAP 241_ TISPL 246_ NTSYR 251_ SGENL 256_ NLSCH 261_ AASNP 266_ PAQYS 271_ WFVNG 276_ TFQQS 281_ TQELF 286_ IPNIT 291_ VNNSG 296_ SYTCQ 301_ AHNSD 306_ TGLNR 311_ TTVTT 316_ ITVYA 321_ EPPKP 326_ FITSN 331_ NSNPV 336_ EDEDA 341_ VALTC 346_ EPEIQ 351_ NTTYL 356_ WWVNN 361_ QSLPV 366_ SPRLQ 371_ LSNDN 376_ RTLTL 381_ LSVTR 386_ NDVGP 391_ YECGI 396_ QNELS 401_ VDHSD 406_ PVILN 411_ VLYGP 416_ DDPTI 421_ SPSYT 426_ YYRPG 431_ VNLSL 436_ SCHAA 441_ SNPPA 446_ QYSWL 451_ IDGNI 456_ QQHTQ 461_ ELFIS 466_ NITEK 471_ NSGLY 476_ TCQAN 481_ NSASG 486_ HSRTT 491_ VKTIT 496_ VSAEL 501_ PKPSI 506_ SSNNS 511_ KPVED 516_ KDAVA 521_ FTCEP 526_ EAQNT 531_ TYLWW 536_ VNGQS 541_ LPVSP 546_ RLQLS 551_ NGNRT 556_ LTLFN 561_ VTRND 566_ ARAYV 571_ CGIQN 576_ SVSAN 581_ RSDPV 586_ TLDVL 591_ YGPDT 596_ PIISP 601_ PDSSY 606_ LSGAN 611_ LNLSC 616_ HSASN 621_ PSPQY 626_ SWRIN 631_ GIPQQ 636_ HTQVL 641_ FIAKI 646_ TPNNN 651_ GTYAC 656_ FVSNL 661_ ATGRN 666_ NSIVK 671_ SITVS 676_ ASGTS 681_ PGLSA 686_ GATVG 691_ IMIGV 696_LVGVA
1: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050)
2: (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer