Kallikrein-1 (EC 3.4.21.35) (Kidney/pancreas/salivary gland kallikrein) (Tissue kallikrein)
1_MWFLV 6_ LCLAL 11_ SLGGT 16_ GAAPP 21_ IQSRI 26_ VGGWE 31_ CEQHS 36_ QPWQA 41_ ALYHF 46_ STFQC 51_ GGILV 56_ HRQWV 61_ LTAAH 66_ CISDN 71_ YQLWL 76_ GRHNL 81_ FDDEN 86_ TAQFV 91_ HVSES 96_ FPHPG 101_ FNMSL 106_ LENHT 111_ RQADE 116_ DYSHD 121_ LMLLR 126_ LTEPA 131_ DTITD 136_ AVKVV 141_ ELPTE 146_ EPEVG 151_ STCLA 156_ SGWGS 161_ IEPEN 166_ FSFPD 171_ DLQCV 176_ DLKIL 181_ PNDEC 186_ KKAHV 191_ QKVTD 196_ FMLCV 201_ GHLEG 206_ GKDTC 211_ VGDSG 216_ GPLMC 221_ DGVLQ 226_ GVTSW 231_ GYVPC 236_ GTPNK 241_ PSVAV 246_ RVLSY 251_ VKWIE 256_DTIAE
1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin
2: (Microbial infection) Cleaves Neisseria meningitidis NHBA in saliva; Neisseria is an obligate commensal of the nasopharyngeal mucosa