Gene name: TPO

Uniprot entry:

P07202

Protein names:

Thyroid peroxidase (TPO) (EC 1.11.1.8)

Protein sequence:

1_MRALA 6_ VLSVT 11_ LVMAC 16_ TEAFF 21_ PFISR 26_ GKELL 31_ WGKPE 36_ ESRVS 41_ SVLEE 46_ SKRLV 51_ DTAMY 56_ ATMQR 61_ NLKKR 66_ GILSP 71_ AQLLS 76_ FSKLP 81_ EPTSG 86_ VIARA 91_ AEIME 96_ TSIQA 101_ MKRKV 106_ NLKTQ 111_ QSQHP 116_ TDALS 121_ EDLLS 126_ IIANM 131_ SGCLP 136_ YMLPP 141_ KCPNT 146_ CLANK 151_ YRPIT 156_ GACNN 161_ RDHPR 166_ WGASN 171_ TALAR 176_ WLPPV 181_ YEDGF 186_ SQPRG 191_ WNPGF 196_ LYNGF 201_ PLPPV 206_ REVTR 211_ HVIQV 216_ SNEVV 221_ TDDDR 226_ YSDLL 231_ MAWGQ 236_ YIDHD 241_ IAFTP 246_ QSTSK 251_ AAFGG 256_ GADCQ 261_ MTCEN 266_ QNPCF 271_ PIQLP 276_ EEARP 281_ AAGTA 286_ CLPFY 291_ RSSAA 296_ CGTGD 301_ QGALF 306_ GNLST 311_ ANPRQ 316_ QMNGL 321_ TSFLD 326_ ASTVY 331_ GSSPA 336_ LERQL 341_ RNWTS 346_ AEGLL 351_ RVHAR 356_ LRDSG 361_ RAYLP 366_ FVPPR 371_ APAAC 376_ APEPG 381_ IPGET 386_ RGPCF 391_ LAGDG 396_ RASEV 401_ PSLTA 406_ LHTLW 411_ LREHN 416_ RLAAA 421_ LKALN 426_ AHWSA 431_ DAVYQ 436_ EARKV 441_ VGALH 446_ QIITL 451_ RDYIP 456_ RILGP 461_ EAFQQ 466_ YVGPY 471_ EGYDS 476_ TANPT 481_ VSNVF 486_ STAAF 491_ RFGHA 496_ TIHPL 501_ VRRLD 506_ ASFQE 511_ HPDLP 516_ GLWLH 521_ QAFFS 526_ PWTLL 531_ RGGGL 536_ DPLIR 541_ GLLAR 546_ PAKLQ 551_ VQDQL 556_ MNEEL 561_ TERLF 566_ VLSNS 571_ STLDL 576_ ASINL 581_ QRGRD 586_ HGLPG 591_ YNEWR 596_ EFCGL 601_ PRLET 606_ PADLS 611_ TAIAS 616_ RSVAD 621_ KILDL 626_ YKHPD 631_ NIDVW 636_ LGGLA 641_ ENFLP 646_ RARTG 651_ PLFAC 656_ LIGKQ 661_ MKALR 666_ DGDWF 671_ WWENS 676_ HVFTD 681_ AQRRE 686_ LEKHS 691_ LSRVI 696_ CDNTG 701_ LTRVP 706_ MDAFQ 711_ VGKFP 716_ EDFES 721_ CDSIT 726_ GMNLE 731_ AWRET 736_ FPQDD 741_ KCGFP 746_ ESVEN 751_ GDFVH 756_ CEESG 761_ RRVLV 766_ YSCRH 771_ GYELQ 776_ GREQL 781_ TCTQE 786_ GWDFQ 791_ PPLCK 796_ DVNEC 801_ ADGAH 806_ PPCHA 811_ SARCR 816_ NTKGG 821_ FQCLC 826_ ADPYE 831_ LGDDG 836_ RTCVD 841_ SGRLP 846_ RVTWI 851_ SMSLA 856_ ALLIG 861_ GFAGL 866_ TSTVI 871_ CRWTR 876_ TGTKS 881_ TLPIS 886_ ETGGG 891_ TPELR 896_ CGKHQ 901_ AVGTS 906_ PQRAA 911_ AQDSE 916_ QESAG 921_ MEGRD 926_THRLP

Protein annotations

Protein functions:

1: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4)