Asialoglycoprotein receptor 1 (ASGP-R 1) (ASGPR 1) (C-type lectin domain family 4 member H1) (Hepatic lectin H1) (HL-1)
1_MTKEY 6_ QDLQH 11_ LDNEE 16_ SDHHQ 21_ LRKGP 26_ PPPQP 31_ LLQRL 36_ CSGPR 41_ LLLLS 46_ LGLSL 51_ LLLVV 56_ VCVIG 61_ SQNSQ 66_ LQEEL 71_ RGLRE 76_ TFSNF 81_ TASTE 86_ AQVKG 91_ LSTQG 96_ GNVGR 101_ KMKSL 106_ ESQLE 111_ KQQKD 116_ LSEDH 121_ SSLLL 126_ HVKQF 131_ VSDLR 136_ SLSCQ 141_ MAALQ 146_ GNGSE 151_ RTCCP 156_ VNWVE 161_ HERSC 166_ YWFSR 171_ SGKAW 176_ ADADN 181_ YCRLE 186_ DAHLV 191_ VVTSW 196_ EEQKF 201_ VQHHI 206_ GPVNT 211_ WMGLH 216_ DQNGP 221_ WKWVD 226_ GTDYE 231_ TGFKN 236_ WRPEQ 241_ PDDWY 246_ GHGLG 251_ GGEDC 256_ AHFTD 261_ DGRWN 266_ DDVCQ 271_ RPYRW 276_ VCETE 281_ LDKAS 286_QEPPL
1: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface