POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)
1_MVHSS 6_ MGAPE 11_ IRMSK 16_ PLEAE 21_ KQGLD 26_ SPSEH 31_ TDTER 36_ NGPDT 41_ NHQNP 46_ QNKTS 51_ PFSVS 56_ PTGPS 61_ TKIKA 66_ EDPSG 71_ DSAPA 76_ APLPP 81_ QPAQP 86_ HLPQA 91_ QLMLT 96_ GSQLA 101_ GDIQQ 106_ LLQLQ 111_ QLVLV 116_ PGHHL 121_ QPPAQ 126_ FLLPQ 131_ AQQSQ 136_ PGLLP 141_ TPNLF 146_ QLPQQ 151_ TQGAL 156_ LTSQP 161_ RAGLP 166_ TQAVT 171_ RPTLP 176_ DPHLS 181_ HPQPP 186_ KCLEP 191_ PSHPE 196_ EPSDL 201_ EELEQ 206_ FARTF 211_ KQRRI 216_ KLGFT 221_ QGDVG 226_ LAMGK 231_ LYGND 236_ FSQTT 241_ ISRFE 246_ ALNLS 251_ FKNMC 256_ KLKPL 261_ LEKWL 266_ NDAET 271_ MSVDS 276_ SLPSP 281_ NQLSS 286_ PSLGF 291_ DGLPG 296_ RRRKK 301_ RTSIE 306_ TNVRF 311_ ALEKS 316_ FLANQ 321_ KPTSE 326_ EILLI 331_ AEQLH 336_ MEKEV 341_ IRVWF 346_ CNRRQ 351_ KEKRI 356_ NPCSA 361_ APMLP 366_ SPGKP 371_ ASYSP 376_ HMVTP 381_ QGGAG 386_ TLPLS 391_ QASSS 396_ LSTTV 401_ TTLSS 406_ AVGTL 411_ HPSRT 416_ AGGGG 421_ GGGGA 426_ APPLN 431_ SIPSV 436_ TPPPP 441_ ATTNS 446_ TNPSP 451_ QGSHS 456_ AIGLS 461_ GLNPS 466_ TGPGL 471_WWNPA
1: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874)
2: Activates the U2 small nuclear RNA (snRNA) promoter