Gene name: GSTP1

Uniprot entry:

P09211

Protein names:

Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1)

Protein sequence:

1_MPPYT 6_ VVYFP 11_ VRGRC 16_ AALRM 21_ LLADQ 26_ GQSWK 31_ EEVVT 36_ VETWQ 41_ EGSLK 46_ ASCLY 51_ GQLPK 56_ FQDGD 61_ LTLYQ 66_ SNTIL 71_ RHLGR 76_ TLGLY 81_ GKDQQ 86_ EAALV 91_ DMVND 96_ GVEDL 101_ RCKYI 106_ SLIYT 111_ NYEAG 116_ KDDYV 121_ KALPG 126_ QLKPF 131_ ETLLS 136_ QNQGG 141_ KTFIV 146_ GDQIS 151_ FADYN 156_ LLDLL 161_ LIHEV 166_ LAPGC 171_ LDAFP 176_ LLSAY 181_ VGRLS 186_ ARPKL 191_ KAFLA 196_ SPEYV 201_NLPIN

Protein annotations

Protein functions:

1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration