Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
1_MACGL 6_ VASNL 11_ NLKPG 16_ ECLRV 21_ RGEVA 26_ PDAKS 31_ FVLNL 36_ GKDSN 41_ NLCLH 46_ FNPRF 51_ NAHGD 56_ ANTIV 61_ CNSKD 66_ GGAWG 71_ TEQRE 76_ AVFPF 81_ QPGSV 86_ AEVCI 91_ TFDQA 96_ NLTVK 101_ LPDGY 106_ EFKFP 111_ NRLNL 116_ EAINY 121_ MAADG 126_DFKIK
1: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69 (PubMed:24752896)