Gene name: KRTAP1-4

Uniprot entry:

P0C5Y4

Protein names:

Keratin-associated protein 1-4 (High sulfur keratin-associated protein 1.4) (Keratin-associated protein 1.4)

Protein sequence:

1_MASCS 6_ TSGTC 11_ GSSCC 16_ QPSCC 21_ ETSCC 26_ QPSCC 31_ QTSSC 36_ GTGCG 41_ IGGGI 46_ GYGQE 51_ GSGGS 56_ VSTRI 61_ RWCHP 66_ DCHVE 71_ GTCLP 76_ PCYLV 81_ SCTPP 86_ SCCQL 91_ HHAEA 96_ SCCRP 101_ SYCGQ 106_ SCCRP 111_ ACCCH 116_CCEPT

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins