Gene name: PIRT

Uniprot entry:

P0C851

Protein names:

Phosphoinositide-interacting protein

Protein sequence:

1_MTMET 6_ LPKVL 11_ EVDEK 16_ SPEAK 21_ DLLPS 26_ QTASS 31_ LCISS 36_ RSESV 41_ WTTTP 46_ RSNWE 51_ IYRKP 56_ IVIMS 61_ VGGAI 66_ LLFGV 71_ VITCL 76_ AYTLK 81_ LSDKS 86_ LSILK 91_ MVGPG 96_ FLSLG 101_ LMMLV 106_ CGLVW 111_ VPIIK 116_ KKQKH 121_ RQKSN 126_ FLRSL 131_KSFFL

Protein annotations

Protein functions:

1: Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity)