Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup)
1_MLRST 6_ STVTL 11_ LSGGA 16_ ARTPG 21_ APSRR 26_ ANVCR 31_ LRLTV 36_ PPESP 41_ VPEQC 46_ EKKIE 51_ RKEQL 56_ LDLSN 61_ GEPTR 66_ KLPQG 71_ VVYGV 76_ VRRSD 81_ QNQQK 86_ EMVVY 91_ GWSTS 96_ QLKEE 101_ MNYIK 106_ DVRAT 111_ LEKVR 116_ KRMYG 121_ DYDEM 126_ RQKIR 131_ QLTQE 136_ LSVSH 141_ AQQEY 146_ LENHI 151_ QTQSS 156_ ALDRF 161_ NAMNS 166_ ALASD 171_ SIGLQ 176_ KTLVD 181_ VTLEN 186_ SNIKD 191_ QIRNL 196_ QQTYE 201_ ASMDK 206_ LREKQ 211_ RQLEV 216_ AQVEN 221_ QLLKM 226_ KVESS 231_ QEANA 236_ EVMRE 241_ MTKKL 246_ YSQYE 251_ EKLQE 256_ EQRKH 261_ SAEKE 266_ ALLEE 271_ TNSFL 276_ KAIEE 281_ ANKKM 286_ QAAEI 291_ SLEEK 296_ DQRIG 301_ ELDRL 306_ IERME 311_ KERHQ 316_ LQLQL 321_ LEHET 326_ EMSGE 331_ LTDSD 336_ KERYQ 341_ QLEEA 346_ SASLR 351_ ERIRH 356_ LDDMV 361_ HCQQK 366_ KVKQM 371_ VEEIE 376_ SLKKK 381_ LQQKQ 386_ LLILQ 391_ LLEKI 396_ SFLEG 401_ ENNEL 406_ QSRLD 411_ YLTET 416_ QAKTE 421_ VETRE 426_ IGVGC 431_ DLLPS 436_ QTGRT 441_ REIVM 446_ PSRNY 451_ TPYTR 456_ VLELT 461_MKKTL
1: Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity)