Gene name: MRLN

Uniprot entry:

P0DMT0

Protein names:

Myoregulin

Protein sequence:

1_MTGKN 6_ WILIS 11_ TTTPK 16_ SLEDE 21_ IVGRL 26_ LKILF 31_ VIFVD 36_ LISII 41_YVVIT

Protein annotations

Protein functions:

1: Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle. Also inhibits the activity of ATP2A2/SERCA2 and ATP2A3/SERCA3