Neuropeptide Y receptor type 4-2
1_MNTSH 6_ LLALL 11_ LPKSP 16_ QGENR 21_ SKPLG 26_ TPYNF 31_ SEHCQ 36_ DSVDV 41_ MVFIV 46_ TSYSI 51_ ETVVG 56_ VLGNL 61_ CLMCV 66_ TVRQK 71_ EKANV 76_ TNLLI 81_ ANLAF 86_ SDFLM 91_ CLLCQ 96_ PLTAV 101_ YTIMD 106_ YWIFG 111_ ETLCK 116_ MSAFI 121_ QCMSV 126_ TVSIL 131_ SLVLV 136_ ALERH 141_ QLIIN 146_ PTGWK 151_ PSISQ 156_ AYLGI 161_ VLIWV 166_ IACVL 171_ SLPFL 176_ ANSIL 181_ ENVFH 186_ KNHSK 191_ ALEFL 196_ ADKVV 201_ CTESW 206_ PLAHH 211_ RTIYT 216_ TFLLL 221_ FQYCL 226_ PLGFI 231_ LVCYA 236_ RIYRR 241_ LQRQG 246_ RVFHK 251_ GTYSL 256_ RAGHM 261_ KQVNV 266_ VLVVM 271_ VVAFA 276_ VLWLP 281_ LHVFN 286_ SLEDW 291_ HHEAI 296_ PICHG 301_ NLIFL 306_ VCHLL 311_ AMAST 316_ CVNPF 321_ IYGFL 326_ NTNFK 331_ KEIKA 336_ LVLTC 341_ QQSAP 346_ LEESE 351_ HLPLS 356_ TVHTE 361_ VSKGS 366_LRLSG
1: G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP. The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid