Gene name: CALCB

Uniprot entry:

P10092

Protein names:

Calcitonin gene-related peptide 2 (Beta-type CGRP) (Beta-CGRP) (Calcitonin gene-related peptide II) (CGRP-II)

Protein sequence:

1_MGFRK 6_ FSPFL 11_ ALSIL 16_ VLYQA 21_ GSLQA 26_ APFRS 31_ ALESS 36_ PDPAT 41_ LSKED 46_ ARLLL 51_ AALVQ 56_ DYVQM 61_ KASEL 66_ KQEQE 71_ TQGSS 76_ SAAQK 81_ RACNT 86_ ATCVT 91_ HRLAG 96_ LLSRS 101_ GGMVK 106_ SNFVP 111_ TNVGS 116_ KAFGR 121_RRRDL

Protein annotations

Protein functions:

1: CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed:3492492)