Gene name: H1-4

Uniprot entry:

P10412

Protein names:

Histone H1.4 (Histone H1b) (Histone H1s-4)

Protein sequence:

1_MSETA 6_ PAAPA 11_ APAPA 16_ EKTPV 21_ KKKAR 26_ KSAGA 31_ AKRKA 36_ SGPPV 41_ SELIT 46_ KAVAA 51_ SKERS 56_ GVSLA 61_ ALKKA 66_ LAAAG 71_ YDVEK 76_ NNSRI 81_ KLGLK 86_ SLVSK 91_ GTLVQ 96_ TKGTG 101_ ASGSF 106_ KLNKK 111_ AASGE 116_ AKPKA 121_ KKAGA 126_ AKAKK 131_ PAGAA 136_ KKPKK 141_ ATGAA 146_ TPKKS 151_ AKKTP 156_ KKAKK 161_ PAAAA 166_ GAKKA 171_ KSPKK 176_ AKAAK 181_ PKKAP 186_ KSPAK 191_ AKAVK 196_ PKAAK 201_ PKTAK 206_ PKAAK 211_PKKAA

Protein annotations

Protein functions:

1: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity)