Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin)
1_MRIAV 6_ ICFCL 11_ LGITC 16_ AIPVK 21_ QADSG 26_ SSEEK 31_ QLYNK 36_ YPDAV 41_ ATWLN 46_ PDPSQ 51_ KQNLL 56_ APQNA 61_ VSSEE 66_ TNDFK 71_ QETLP 76_ SKSNE 81_ SHDHM 86_ DDMDD 91_ EDDDD 96_ HVDSQ 101_ DSIDS 106_ NDSDD 111_ VDDTD 116_ DSHQS 121_ DESHH 126_ SDESD 131_ ELVTD 136_ FPTDL 141_ PATEV 146_ FTPVV 151_ PTVDT 156_ YDGRG 161_ DSVVY 166_ GLRSK 171_ SKKFR 176_ RPDIQ 181_ YPDAT 186_ DEDIT 191_ SHMES 196_ EELNG 201_ AYKAI 206_ PVAQD 211_ LNAPS 216_ DWDSR 221_ GKDSY 226_ ETSQL 231_ DDQSA 236_ ETHSH 241_ KQSRL 246_ YKRKA 251_ NDESN 256_ EHSDV 261_ IDSQE 266_ LSKVS 271_ REFHS 276_ HEFHS 281_ HEDML 286_ VVDPK 291_ SKEED 296_ KHLKF 301_ RISHE 306_LDSAS
1: Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction
2: Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity