Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
1_MAPEP 6_ APGRT 11_ MVPLV 16_ PALVM 21_ LGLVA 26_ GAHGD 31_ SKPVF 36_ IKVPE 41_ DQTGL 46_ SGGVA 51_ SFVCQ 56_ ATGEP 61_ KPRIT 66_ WMKKG 71_ KKVSS 76_ QRFEV 81_ IEFDD 86_ GAGSV 91_ LRIQP 96_ LRVQR 101_ DEAIY 106_ ECTAT 111_ NSLGE 116_ INTSA 121_ KLSVL 126_ EEEQL 131_ PPGFP 136_ SIDMG 141_ PQLKV 146_ VEKAR 151_ TATML 156_ CAAGG 161_ NPDPE 166_ ISWFK 171_ DFLPV 176_ DPATS 181_ NGRIK 186_ QLRSG 191_ ALQIE 196_ SSEES 201_ DQGKY 206_ ECVAT 211_ NSAGT 216_ RYSAP 221_ ANLYV 226_ RVRRV 231_ APRFS 236_ IPPSS 241_ QEVMP 246_ GGSVN 251_ LTCVA 256_ VGAPM 261_ PYVKW 266_ MMGAE 271_ ELTKE 276_ DEMPV 281_ GRNVL 286_ ELSNV 291_ VRSAN 296_ YTCVA 301_ ISSLG 306_ MIEAT 311_ AQVTV 316_ KALPK 321_ PPIDL 326_ VVTET 331_ TATSV 336_ TLTWD 341_ SGNSE 346_ PVTYY 351_ GIQYR 356_ AAGTE 361_ GPFQE 366_ VDGVA 371_ TTRYS 376_ IGGLS 381_ PFSEY 386_ AFRVL 391_ AVNSI 396_ GRGPP 401_ SEAVR 406_ ARTGE 411_ QAPSS 416_ PPRRV 421_ QARML 426_ SASTM 431_ LVQWE 436_ PPEEP 441_ NGLVR 446_ GYRVY 451_ YTPDS 456_ RRPPN 461_ AWHKH 466_ NTDAG 471_ LLTTV 476_ GSLLP 481_ GITYS 486_ LRVLA 491_ FTAVG 496_ DGPPS 501_ PTIQV 506_ KTQQG 511_ VPAQP 516_ ADFQA 521_ EVESD 526_ TRIQL 531_ SWLLP 536_ PQERI 541_ IMYEL 546_ VYWAA 551_ EDEDQ 556_ QHKVT 561_ FDPTS 566_ SYTLE 571_ DLKPD 576_ TLYRF 581_ QLAAR 586_ SDMGV 591_ GVFTP 596_ TIEAR 601_ TAQST 606_ PSAPP 611_ QKVMC 616_ VSMGS 621_ TTVRV 626_ SWVPP 631_ PADSR 636_ NGVIT 641_ QYSVA 646_ YEAVD 651_ GEDRG 656_ RHVVD 661_ GISRE 666_ HSSWD 671_ LVGLE 676_ KWTEY 681_ RVWVR 686_ AHTDV 691_ GPGPE 696_ SSPVL 701_ VRTDE 706_ DVPSG 711_ PPRKV 716_ EVEPL 721_ NSTAV 726_ HVYWK 731_ LPVPS 736_ KQHGQ 741_ IRGYQ 746_ VTYVR 751_ LENGE 756_ PRGLP 761_ IIQDV 766_ MLAEA 771_ QWRPE 776_ ESEDY 781_ ETTIS 786_ GLTPE 791_ TTYSV 796_ TVAAY 801_ TTKGD 806_ GARSK 811_ PKIVT 816_ TTGAV 821_ PGRPT 826_ MMIST 831_ TAMNT 836_ ALLQW 841_ HPPKE 846_ LPGEL 851_ LGYRL 856_ QYCRA 861_ DEARP 866_ NTIDF 871_ GKDDQ 876_ HFTVT 881_ GLHKG 886_ TTYIF 891_ RLAAK 896_ NRAGL 901_ GEEFE 906_ KEIRT 911_ PEDLP 916_ SGFPQ 921_ NLHVT 926_ GLTTS 931_ TTELA 936_ WDPPV 941_ LAERN 946_ GRIIS 951_ YTVVF 956_ RDINS 961_ QQELQ 966_ NITTD 971_ TRFTL 976_ TGLKP 981_ DTTYD 986_ IKVRA 991_ WTSKG 996_ SGPLS 1001_ PSIQS 1006_ RTMPV 1011_ EQVFA 1016_ KNFRV 1021_ AAAMK 1026_ TSVLL 1031_ SWEVP 1036_ DSYKS 1041_ AVPFK 1046_ ILYNG 1051_ QSVEV 1056_ DGHSM 1061_ RKLIA 1066_ DLQPN 1071_ TEYSF 1076_ VLMNR 1081_ GSSAG 1086_ GLQHL 1091_ VSIRT 1096_ APDLL 1101_ PHKPL 1106_ PASAY 1111_ IEDGR 1116_ FDLSM 1121_ PHVQD 1126_ PSLVR 1131_ WFYIV 1136_ VVPID 1141_ RVGGS 1146_ MLTPR 1151_ WSTPE 1156_ ELELD 1161_ ELLEA 1166_ IEQGG 1171_ EEQRR 1176_ RRRQA 1181_ ERLKP 1186_ YVAAQ 1191_ LDVLP 1196_ ETFTL 1201_ GDKKN 1206_ YRGFY 1211_ NRPLS 1216_ PDLSY 1221_ QCFVL 1226_ ASLKE 1231_ PMDQK 1236_ RYASS 1241_ PYSDE 1246_ IVVQV 1251_ TPAQQ 1256_ QEEPE 1261_ MLWVT 1266_ GPVLA 1271_ VILII 1276_ LIVIA 1281_ ILLFK 1286_ RKRTH 1291_ SPSSK 1296_ DEQSI 1301_ GLKDS 1306_ LLAHS 1311_ SDPVE 1316_ MRRLN 1321_ YQTPG 1326_ MRDHP 1331_ PIPIT 1336_ DLADN 1341_ IERLK 1346_ ANDGL 1351_ KFSQE 1356_ YESID 1361_ PGQQF 1366_ TWENS 1371_ NLEVN 1376_ KPKNR 1381_ YANVI 1386_ AYDHS 1391_ RVILT 1396_ SIDGV 1401_ PGSDY 1406_ INANY 1411_ IDGYR 1416_ KQNAY 1421_ IATQG 1426_ PLPET 1431_ MGDFW 1436_ RMVWE 1441_ QRTAT 1446_ VVMMT 1451_ RLEEK 1456_ SRVKC 1461_ DQYWP 1466_ ARGTE 1471_ TCGLI 1476_ QVTLL 1481_ DTVEL 1486_ ATYTV 1491_ RTFAL 1496_ HKSGS 1501_ SEKRE 1506_ LRQFQ 1511_ FMAWP 1516_ DHGVP 1521_ EYPTP 1526_ ILAFL 1531_ RRVKA 1536_ CNPLD 1541_ AGPMV 1546_ VHCSA 1551_ GVGRT 1556_ GCFIV 1561_ IDAML 1566_ ERMKH 1571_ EKTVD 1576_ IYGHV 1581_ TCMRS 1586_ QRNYM 1591_ VQTED 1596_ QYVFI 1601_ HEALL 1606_ EAATC 1611_ GHTEV 1616_ PARNL 1621_ YAHIQ 1626_ KLGQV 1631_ PPGES 1636_ VTAME 1641_ LEFKL 1646_ LASSK 1651_ AHTSR 1656_ FISAN 1661_ LPCNK 1666_ FKNRL 1671_ VNIMP 1676_ YELTR 1681_ VCLQP 1686_ IRGVE 1691_ GSDYI 1696_ NASFL 1701_ DGYRQ 1706_ QKAYI 1711_ ATQGP 1716_ LAEST 1721_ EDFWR 1726_ MLWEH 1731_ NSTII 1736_ VMLTK 1741_ LREMG 1746_ REKCH 1751_ QYWPA 1756_ ERSAR 1761_ YQYFV 1766_ VDPMA 1771_ EYNMP 1776_ QYILR 1781_ EFKVT 1786_ DARDG 1791_ QSRTI 1796_ RQFQF 1801_ TDWPE 1806_ QGVPK 1811_ TGEGF 1816_ IDFIG 1821_ QVHKT 1826_ KEQFG 1831_ QDGPI 1836_ TVHCS 1841_ AGVGR 1846_ TGVFI 1851_ TLSIV 1856_ LERMR 1861_ YEGVV 1866_ DMFQT 1871_ VKTLR 1876_ TQRPA 1881_ MVQTE 1886_ DQYQL 1891_ CYRAA 1896_ LEYLG 1901_SFDHY
1: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity
2: The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one