Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)
1_MEPSS 6_ KKLTG 11_ RLMLA 16_ VGGAV 21_ LGSLQ 26_ FGYNT 31_ GVINA 36_ PQKVI 41_ EEFYN 46_ QTWVH 51_ RYGES 56_ ILPTT 61_ LTTLW 66_ SLSVA 71_ IFSVG 76_ GMIGS 81_ FSVGL 86_ FVNRF 91_ GRRNS 96_ MLMMN 101_ LLAFV 106_ SAVLM 111_ GFSKL 116_ GKSFE 121_ MLILG 126_ RFIIG 131_ VYCGL 136_ TTGFV 141_ PMYVG 146_ EVSPT 151_ ALRGA 156_ LGTLH 161_ QLGIV 166_ VGILI 171_ AQVFG 176_ LDSIM 181_ GNKDL 186_ WPLLL 191_ SIIFI 196_ PALLQ 201_ CIVLP 206_ FCPES 211_ PRFLL 216_ INRNE 221_ ENRAK 226_ SVLKK 231_ LRGTA 236_ DVTHD 241_ LQEMK 246_ EESRQ 251_ MMREK 256_ KVTIL 261_ ELFRS 266_ PAYRQ 271_ PILIA 276_ VVLQL 281_ SQQLS 286_ GINAV 291_ FYYST 296_ SIFEK 301_ AGVQQ 306_ PVYAT 311_ IGSGI 316_ VNTAF 321_ TVVSL 326_ FVVER 331_ AGRRT 336_ LHLIG 341_ LAGMA 346_ GCAIL 351_ MTIAL 356_ ALLEQ 361_ LPWMS 366_ YLSIV 371_ AIFGF 376_ VAFFE 381_ VGPGP 386_ IPWFI 391_ VAELF 396_ SQGPR 401_ PAAIA 406_ VAGFS 411_ NWTSN 416_ FIVGM 421_ CFQYV 426_ EQLCG 431_ PYVFI 436_ IFTVL 441_ LVLFF 446_ IFTYF 451_ KVPET 456_ KGRTF 461_ DEIAS 466_ GFRQG 471_ GASQS 476_ DKTPE 481_ ELFHP 486_LGADS
1: Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:10227690, PubMed:10954735, PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:32860739). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed:10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity)