Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)
1_MGCGT 6_ SKVLP 11_ EPPKD 16_ VQLDL 21_ VKKVE 26_ PFSGT 31_ KSDVY 36_ KHFIT 41_ EVDSV 46_ GPVKA 51_ GFPAA 56_ SQYAH 61_ PCPGP 66_ PTAGH 71_ TEPPS 76_ EPPRR 81_ ARVAK 86_ YRAKF 91_ DPRVT 96_ AKYDI 101_ KALIG 106_ RGSFS 111_ RVVRV 116_ EHRAT 121_ RQPYA 126_ IKMIE 131_ TKYRE 136_ GREVC 141_ ESELR 146_ VLRRV 151_ RHANI 156_ IQLVE 161_ VFETQ 166_ ERVYM 171_ VMELA 176_ TGGEL 181_ FDRII 186_ AKGSF 191_ TERDA 196_ TRVLQ 201_ MVLDG 206_ VRYLH 211_ ALGIT 216_ HRDLK 221_ PENLL 226_ YYHPG 231_ TDSKI 236_ IITDF 241_ GLASA 246_ RKKGD 251_ DCLMK 256_ TTCGT 261_ PEYIA 266_ PEVLV 271_ RKPYT 276_ NSVDM 281_ WALGV 286_ IAYIL 291_ LSGTM 296_ PFEDD 301_ NRTRL 306_ YRQIL 311_ RGKYS 316_ YSGEP 321_ WPSVS 326_ NLAKD 331_ FIDRL 336_ LTVDP 341_ GARMT 346_ ALQAL 351_ RHPWV 356_ VSMAA 361_ SSSMK 366_ NLHRS 371_ ISQNL 376_ LKRAS 381_ SRCQS 386_ TKSAQ 391_ STRSS 396_ RSTRS 401_ NKSRR 406_ VRERE 411_ LRELN 416_LRYQQ
1: Serine/threonine protein kinase that may be involved in the regulation of pre-mRNA processing. It may phosphorylate components of nuclear splice factor compartments (SFC), such as non-snRNP splicing factors containing a serine/arginine-rich domain (SR proteins). Reversible phosphorylation of SR proteins may cause their release into the nucleoplasm and change their local concentration, thereby influencing alternative splicing