Ornithine decarboxylase (ODC) (EC 4.1.1.17)
1_MNNFG 6_ NEEFD 11_ CHFLD 16_ EGFTA 21_ KDILD 26_ QKINE 31_ VSSSD 36_ DKDAF 41_ YVADL 46_ GDILK 51_ KHLRW 56_ LKALP 61_ RVTPF 66_ YAVKC 71_ NDSKA 76_ IVKTL 81_ AATGT 86_ GFDCA 91_ SKTEI 96_ QLVQS 101_ LGVPP 106_ ERIIY 111_ ANPCK 116_ QVSQI 121_ KYAAN 126_ NGVQM 131_ MTFDS 136_ EVELM 141_ KVARA 146_ HPKAK 151_ LVLRI 156_ ATDDS 161_ KAVCR 166_ LSVKF 171_ GATLR 176_ TSRLL 181_ LERAK 186_ ELNID 191_ VVGVS 196_ FHVGS 201_ GCTDP 206_ ETFVQ 211_ AISDA 216_ RCVFD 221_ MGAEV 226_ GFSMY 231_ LLDIG 236_ GGFPG 241_ SEDVK 246_ LKFEE 251_ ITGVI 256_ NPALD 261_ KYFPS 266_ DSGVR 271_ IIAEP 276_ GRYYV 281_ ASAFT 286_ LAVNI 291_ IAKKI 296_ VLKEQ 301_ TGSDD 306_ EDESS 311_ EQTFM 316_ YYVND 321_ GVYGS 326_ FNCIL 331_ YDHAH 336_ VKPLL 341_ QKRPK 346_ PDEKY 351_ YSSSI 356_ WGPTC 361_ DGLDR 366_ IVERC 371_ DLPEM 376_ HVGDW 381_ MLFEN 386_ MGAYT 391_ VAAAS 396_ TFNGF 401_ QRPTI 406_ YYVMS 411_ GPAWQ 416_ LMQQF 421_ QNPDF 426_ PPEVE 431_ EQDAS 436_ TLPVS 441_ CAWES 446_ GMKRH 451_ RAACA 456_SASIN
1: Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis