Gene name: RARG

Uniprot entry:

P13631

Protein names:

Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3)

Protein sequence:

1_MATNK 6_ ERLFA 11_ AGALG 16_ PGSGY 21_ PGAGF 26_ PFAFP 31_ GALRG 36_ SPPFE 41_ MLSPS 46_ FRGLG 51_ QPDLP 56_ KEMAS 61_ LSVET 66_ QSTSS 71_ EEMVP 76_ SSPSP 81_ PPPPR 86_ VYKPC 91_ FVCND 96_ KSSGY 101_ HYGVS 106_ SCEGC 111_ KGFFR 116_ RSIQK 121_ NMVYT 126_ CHRDK 131_ NCIIN 136_ KVTRN 141_ RCQYC 146_ RLQKC 151_ FEVGM 156_ SKEAV 161_ RNDRN 166_ KKKKE 171_ VKEEG 176_ SPDSY 181_ ELSPQ 186_ LEELI 191_ TKVSK 196_ AHQET 201_ FPSLC 206_ QLGKY 211_ TTNSS 216_ ADHRV 221_ QLDLG 226_ LWDKF 231_ SELAT 236_ KCIIK 241_ IVEFA 246_ KRLPG 251_ FTGLS 256_ IADQI 261_ TLLKA 266_ ACLDI 271_ LMLRI 276_ CTRYT 281_ PEQDT 286_ MTFSD 291_ GLTLN 296_ RTQMH 301_ NAGFG 306_ PLTDL 311_ VFAFA 316_ GQLLP 321_ LEMDD 326_ TETGL 331_ LSAIC 336_ LICGD 341_ RMDLE 346_ EPEKV 351_ DKLQE 356_ PLLEA 361_ LRLYA 366_ RRRRP 371_ SQPYM 376_ FPRML 381_ MKITD 386_ LRGIS 391_ TKGAE 396_ RAITL 401_ KMEIP 406_ GPMPP 411_ LIREM 416_ LENPE 421_ MFEDD 426_ SSQPG 431_ PHPNA 436_ SSEDE 441_ VPGGQ 446_GKGGL

Protein annotations

Protein functions:

1: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity)