Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
1_MQPQS 6_ VLHSG 11_ YFHPL 16_ LRAWQ 21_ TATTT 26_ LNASN 31_ LIYPI 36_ FVTDV 41_ PDDIQ 46_ PITSL 51_ PGVAR 56_ YGVKR 61_ LEEML 66_ RPLVE 71_ EGLRC 76_ VLIFG 81_ VPSRV 86_ PKDER 91_ GSAAD 96_ SEESP 101_ AIEAI 106_ HLLRK 111_ TFPNL 116_ LVACD 121_ VCLCP 126_ YTSHG 131_ HCGLL 136_ SENGA 141_ FRAEE 146_ SRQRL 151_ AEVAL 156_ AYAKA 161_ GCQVV 166_ APSDM 171_ MDGRV 176_ EAIKE 181_ ALMAH 186_ GLGNR 191_ VSVMS 196_ YSAKF 201_ ASCFY 206_ GPFRD 211_ AAKSS 216_ PAFGD 221_ RRCYQ 226_ LPPGA 231_ RGLAL 236_ RAVDR 241_ DVREG 246_ ADMLM 251_ VKPGM 256_ PYLDI 261_ VREVK 266_ DKHPD 271_ LPLAV 276_ YHVSG 281_ EFAML 286_ WHGAQ 291_ AGAFD 296_ LKAAV 301_ LEAMT 306_ AFRRA 311_ GADII 316_ ITYYT 321_PQLLQ
1: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen