Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B')
1_MTVGK 6_ SSKML 11_ QHIDY 16_ RMRCI 21_ LQDGR 26_ IFIGT 31_ FKAFD 36_ KHMNL 41_ ILCDC 46_ DEFRK 51_ IKPKN 56_ SKQAE 61_ REEKR 66_ VLGLV 71_ LLRGE 76_ NLVSM 81_ TVEGP 86_ PPKDT 91_ GIARV 96_ PLAGA 101_ AGGPG 106_ IGRAA 111_ GRGIP 116_ AGVPM 121_ PQAPA 126_ GLAGP 131_ VRGVG 136_ GPSQQ 141_ VMTPQ 146_ GRGTV 151_ AAAAA 156_ AATAS 161_ IAGAP 166_ TQYPP 171_ GRGGP 176_ PPPMG 181_ RGAPP 186_ PGMMG 191_ PPPGM 196_ RPPMG 201_ PPMGI 206_ PPGRG 211_ TPMGM 216_ PPPGM 221_ RPPPP 226_ GMRGP 231_PPPGM
1: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:12975319)