Protein C-ets-1 (p54)
1_MKAAV 6_ DLKPT 11_ LTIIK 16_ TEKVD 21_ LELFP 26_ SPDME 31_ CADVP 36_ LLTPS 41_ SKEMM 46_ SQALK 51_ ATFSG 56_ FTKEQ 61_ QRLGI 66_ PKDPR 71_ QWTET 76_ HVRDW 81_ VMWAV 86_ NEFSL 91_ KGVDF 96_ QKFCM 101_ NGAAL 106_ CALGK 111_ DCFLE 116_ LAPDF 121_ VGDIL 126_ WEHLE 131_ ILQKE 136_ DVKPY 141_ QVNGV 146_ NPAYP 151_ ESRYT 156_ SDYFI 161_ SYGIE 166_ HAQCV 171_ PPSEF 176_ SEPSF 181_ ITESY 186_ QTLHP 191_ ISSEE 196_ LLSLK 201_ YENDY 206_ PSVIL 211_ RDPLQ 216_ TDTLQ 221_ NDYFA 226_ IKQEV 231_ VTPDN 236_ MCMGR 241_ TSRGK 246_ LGGQD 251_ SFESI 256_ ESYDS 261_ CDRLT 266_ QSWSS 271_ QSSFN 276_ SLQRV 281_ PSYDS 286_ FDSED 291_ YPAAL 296_ PNHKP 301_ KGTFK 306_ DYVRD 311_ RADLN 316_ KDKPV 321_ IPAAA 326_ LAGYT 331_ GSGPI 336_ QLWQF 341_ LLELL 346_ TDKSC 351_ QSFIS 356_ WTGDG 361_ WEFKL 366_ SDPDE 371_ VARRW 376_ GKRKN 381_ KPKMN 386_ YEKLS 391_ RGLRY 396_ YYDKN 401_ IIHKT 406_ AGKRY 411_ VYRFV 416_ CDLQS 421_ LLGYT 426_ PEELH 431_ AMLDV 436_KPDAD
1: Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518)
2: Acts as a dominant-negative for isoform c-ETS-1A