Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
1_MAALS 6_ GGGGG 11_ GAEPG 16_ QALFN 21_ GDMEP 26_ EAGAG 31_ AGAAA 36_ SSAAD 41_ PAIPE 46_ EVWNI 51_ KQMIK 56_ LTQEH 61_ IEALL 66_ DKFGG 71_ EHNPP 76_ SIYLE 81_ AYEEY 86_ TSKLD 91_ ALQQR 96_ EQQLL 101_ ESLGN 106_ GTDFS 111_ VSSSA 116_ SMDTV 121_ TSSSS 126_ SSLSV 131_ LPSSL 136_ SVFQN 141_ PTDVA 146_ RSNPK 151_ SPQKP 156_ IVRVF 161_ LPNKQ 166_ RTVVP 171_ ARCGV 176_ TVRDS 181_ LKKAL 186_ MMRGL 191_ IPECC 196_ AVYRI 201_ QDGEK 206_ KPIGW 211_ DTDIS 216_ WLTGE 221_ ELHVE 226_ VLENV 231_ PLTTH 236_ NFVRK 241_ TFFTL 246_ AFCDF 251_ CRKLL 256_ FQGFR 261_ CQTCG 266_ YKFHQ 271_ RCSTE 276_ VPLMC 281_ VNYDQ 286_ LDLLF 291_ VSKFF 296_ EHHPI 301_ PQEEA 306_ SLAET 311_ ALTSG 316_ SSPSA 321_ PASDS 326_ IGPQI 331_ LTSPS 336_ PSKSI 341_ PIPQP 346_ FRPAD 351_ EDHRN 356_ QFGQR 361_ DRSSS 366_ APNVH 371_ INTIE 376_ PVNID 381_ DLIRD 386_ QGFRG 391_ DGGST 396_ TGLSA 401_ TPPAS 406_ LPGSL 411_ TNVKA 416_ LQKSP 421_ GPQRE 426_ RKSSS 431_ SSEDR 436_ NRMKT 441_ LGRRD 446_ SSDDW 451_ EIPDG 456_ QITVG 461_ QRIGS 466_ GSFGT 471_ VYKGK 476_ WHGDV 481_ AVKML 486_ NVTAP 491_ TPQQL 496_ QAFKN 501_ EVGVL 506_ RKTRH 511_ VNILL 516_ FMGYS 521_ TKPQL 526_ AIVTQ 531_ WCEGS 536_ SLYHH 541_ LHIIE 546_ TKFEM 551_ IKLID 556_ IARQT 561_ AQGMD 566_ YLHAK 571_ SIIHR 576_ DLKSN 581_ NIFLH 586_ EDLTV 591_ KIGDF 596_ GLATV 601_ KSRWS 606_ GSHQF 611_ EQLSG 616_ SILWM 621_ APEVI 626_ RMQDK 631_ NPYSF 636_ QSDVY 641_ AFGIV 646_ LYELM 651_ TGQLP 656_ YSNIN 661_ NRDQI 666_ IFMVG 671_ RGYLS 676_ PDLSK 681_ VRSNC 686_ PKAMK 691_ RLMAE 696_ CLKKK 701_ RDERP 706_ LFPQI 711_ LASIE 716_ LLARS 721_ LPKIH 726_ RSASE 731_ PSLNR 736_ AGFQT 741_ EDFSL 746_ YACAS 751_ PKTPI 756_ QAGGY 761_GAFPV
1: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). Phosphorylates PFKFB2 (PubMed:36402789). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179)