Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
1_MQAIK 6_ CVVVG 11_ DGAVG 16_ KTCLL 21_ ISYTT 26_ NAFPG 31_ EYIPT 36_ VFDNY 41_ SANVM 46_ VDSKP 51_ VNLGL 56_ WDTAG 61_ QEDYD 66_ RLRPL 71_ SYPQT 76_ DVFLI 81_ CFSLV 86_ SPASY 91_ ENVRA 96_ KWFPE 101_ VRHHC 106_ PSTPI 111_ ILVGT 116_ KLDLR 121_ DDKDT 126_ IEKLK 131_ EKKLA 136_ PITYP 141_ QGLAL 146_ AKEID 151_ SVKYL 156_ ECSAL 161_ TQRGL 166_ KTVFD 171_ EAIRA 176_ VLCPQ 181_ PTRQQ 186_KRACS
1: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state (PubMed:30723080). In its active state, binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Regulatory subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)) (PubMed:1660188)