Gene name: AREG

Uniprot entry:

P15514

Protein names:

Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF)

Protein sequence:

1_MRAPL 6_ LPPAP 11_ VVLSL 16_ LILGS 21_ GHYAA 26_ GLDLN 31_ DTYSG 36_ KREPF 41_ SGDHS 46_ ADGFE 51_ VTSRS 56_ EMSSG 61_ SEISP 66_ VSEMP 71_ SSSEP 76_ SSGAD 81_ YDYSE 86_ EYDNE 91_ PQIPG 96_ YIVDD 101_ SVRVE 106_ QVVKP 111_ PQNKT 116_ ESENT 121_ SDKPK 126_ RKKKG 131_ GKNGK 136_ NRRNR 141_ KKKNP 146_ CNAEF 151_ QNFCI 156_ HGECK 161_ YIEHL 166_ EAVTC 171_ KCQQE 176_ YFGER 181_ CGEKS 186_ MKTHS 191_ MIDSS 196_ LSKIA 201_ LAAIA 206_ AFMSA 211_ VILTA 216_ VAVIT 221_ VQLRR 226_ QYVRK 231_ YEGEA 236_ EERKK 241_ LRQEN 246_GNVHA

Protein annotations

Protein functions:

1: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts