Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)
1_MGPRG 6_ AASLP 11_ RGPGP 16_ RRLLL 21_ PVVLP 26_ LLLLL 31_ LLAPP 36_ GSGAG 41_ ASRPP 46_ HLVFL 51_ LADDL 56_ GWNDV 61_ GFHGS 66_ RIRTP 71_ HLDAL 76_ AAGGV 81_ LLDNY 86_ YTQPL 91_ CTPSR 96_ SQLLT 101_ GRYQI 106_ RTGLQ 111_ HQIIW 116_ PCQPS 121_ CVPLD 126_ EKLLP 131_ QLLKE 136_ AGYTT 141_ HMVGK 146_ WHLGM 151_ YRKEC 156_ LPTRR 161_ GFDTY 166_ FGYLL 171_ GSEDY 176_ YSHER 181_ CTLID 186_ ALNVT 191_ RCALD 196_ FRDGE 201_ EVATG 206_ YKNMY 211_ STNIF 216_ TKRAI 221_ ALITN 226_ HPPEK 231_ PLFLY 236_ LALQS 241_ VHEPL 246_ QVPEE 251_ YLKPY 256_ DFIQD 261_ KNRHH 266_ YAGMV 271_ SLMDE 276_ AVGNV 281_ TAALK 286_ SSGLW 291_ NNTVF 296_ IFSTD 301_ NGGQT 306_ LAGGN 311_ NWPLR 316_ GRKWS 321_ LWEGG 326_ VRGVG 331_ FVASP 336_ LLKQK 341_ GVKNR 346_ ELIHI 351_ SDWLP 356_ TLVKL 361_ ARGHT 366_ NGTKP 371_ LDGFD 376_ VWKTI 381_ SEGSP 386_ SPRIE 391_ LLHNI 396_ DPNFV 401_ DSSPC 406_ PRNSM 411_ APAKD 416_ DSSLP 421_ EYSAF 426_ NTSVH 431_ AAIRH 436_ GNWKL 441_ LTGYP 446_ GCGYW 451_ FPPPS 456_ QYNVS 461_ EIPSS 466_ DPPTK 471_ TLWLF 476_ DIDRD 481_ PEERH 486_ DLSRE 491_ YPHIV 496_ TKLLS 501_ RLQFY 506_ HKHSV 511_ PVYFP 516_ AQDPR 521_ CDPKA 526_TGVWG
1: Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity)