Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3)
1_MSETA 6_ PAETA 11_ TPAPV 16_ EKSPA 21_ KKKAT 26_ KKAAG 31_ AGAAK 36_ RKATG 41_ PPVSE 46_ LITKA 51_ VAASK 56_ ERNGL 61_ SLAAL 66_ KKALA 71_ AGGYD 76_ VEKNN 81_ SRIKL 86_ GLKSL 91_ VSKGT 96_ LVQTK 101_ GTGAS 106_ GSFKL 111_ NKKAA 116_ SGEAK 121_ PKAKK 126_ AGAAK 131_ AKKPA 136_ GATPK 141_ KAKKA 146_ AGAKK 151_ AVKKT 156_ PKKAK 161_ KPAAA 166_ GVKKV 171_ AKSPK 176_ KAKAA 181_ AKPKK 186_ ATKSP 191_ AKPKA 196_ VKPKA 201_ AKPKA 206_ AKPKA 211_ AKPKA 216_ AKAKK 221_AAAKK
1: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity)