Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
1_MSETA 6_ PAAPA 11_ AAPPA 16_ EKAPV 21_ KKKAA 26_ KKAGG 31_ TPRKA 36_ SGPPV 41_ SELIT 46_ KAVAA 51_ SKERS 56_ GVSLA 61_ ALKKA 66_ LAAAG 71_ YDVEK 76_ NNSRI 81_ KLGLK 86_ SLVSK 91_ GTLVQ 96_ TKGTG 101_ ASGSF 106_ KLNKK 111_ AASGE 116_ AKPKV 121_ KKAGG 126_ TKPKK 131_ PVGAA 136_ KKPKK 141_ AAGGA 146_ TPKKS 151_ AKKTP 156_ KKAKK 161_ PAAAT 166_ VTKKV 171_ AKSPK 176_ KAKVA 181_ KPKKA 186_ AKSAA 191_ KAVKP 196_ KAAKP 201_ KVVKP 206_KKAAP
1: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity)