Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)
1_MAPPQ 6_ VLAFG 11_ LLLAA 16_ ATATF 21_ AAAQE 26_ ECVCE 31_ NYKLA 36_ VNCFV 41_ NNNRQ 46_ CQCTS 51_ VGAQN 56_ TVICS 61_ KLAAK 66_ CLVMK 71_ AEMNG 76_ SKLGR 81_ RAKPE 86_ GALQN 91_ NDGLY 96_ DPDCD 101_ ESGLF 106_ KAKQC 111_ NGTSM 116_ CWCVN 121_ TAGVR 126_ RTDKD 131_ TEITC 136_ SERVR 141_ TYWII 146_ IELKH 151_ KAREK 156_ PYDSK 161_ SLRTA 166_ LQKEI 171_ TTRYQ 176_ LDPKF 181_ ITSIL 186_ YENNV 191_ ITIDL 196_ VQNSS 201_ QKTQN 206_ DVDIA 211_ DVAYY 216_ FEKDV 221_ KGESL 226_ FHSKK 231_ MDLTV 236_ NGEQL 241_ DLDPG 246_ QTLIY 251_ YVDEK 256_ APEFS 261_ MQGLK 266_ AGVIA 271_ VIVVV 276_ VIAVV 281_ AGIVV 286_ LVISR 291_ KKRMA 296_ KYEKA 301_ EIKEM 306_GEMHR
1: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E