Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
1_MRPAD 6_ LLQLV 11_ LLLDL 16_ PRDLG 21_ GMGCS 26_ SPPCE 31_ CHQEE 36_ DFRVT 41_ CKDIQ 46_ RIPSL 51_ PPSTQ 56_ TLKLI 61_ ETHLR 66_ TIPSH 71_ AFSNL 76_ PNISR 81_ IYVSI 86_ DVTLQ 91_ QLESH 96_ SFYNL 101_ SKVTH 106_ IEIRN 111_ TRNLT 116_ YIDPD 121_ ALKEL 126_ PLLKF 131_ LGIFN 136_ TGLKM 141_ FPDLT 146_ KVYST 151_ DIFFI 156_ LEITD 161_ NPYMT 166_ SIPVN 171_ AFQGL 176_ CNETL 181_ TLKLY 186_ NNGFT 191_ SVQGY 196_ AFNGT 201_ KLDAV 206_ YLNKN 211_ KYLTV 216_ IDKDA 221_ FGGVY 226_ SGPSL 231_ LDVSQ 236_ TSVTA 241_ LPSKG 246_ LEHLK 251_ ELIAR 256_ NTWTL 261_ KKLPL 266_ SLSFL 271_ HLTRA 276_ DLSYP 281_ SHCCA 286_ FKNQK 291_ KIRGI 296_ LESLM 301_ CNESS 306_ MQSLR 311_ QRKSV 316_ NALNS 321_ PLHQE 326_ YEENL 331_ GDSIV 336_ GYKEK 341_ SKFQD 346_ THNNA 351_ HYYVF 356_ FEEQE 361_ DEIIG 366_ FGQEL 371_ KNPQE 376_ ETLQA 381_ FDSHY 386_ DYTIC 391_ GDSED 396_ MVCTP 401_ KSDEF 406_ NPCED 411_ IMGYK 416_ FLRIV 421_ VWFVS 426_ LLALL 431_ GNVFV 436_ LLILL 441_ TSHYK 446_ LNVPR 451_ FLMCN 456_ LAFAD 461_ FCMGM 466_ YLLLI 471_ ASVDL 476_ YTHSE 481_ YYNHA 486_ IDWQT 491_ GPGCN 496_ TAGFF 501_ TVFAS 506_ ELSVY 511_ TLTVI 516_ TLERW 521_ YAITF 526_ AMRLD 531_ RKIRL 536_ RHACA 541_ IMVGG 546_ WVCCF 551_ LLALL 556_ PLVGI 561_ SSYAK 566_ VSICL 571_ PMDTE 576_ TPLAL 581_ AYIVF 586_ VLTLN 591_ IVAFV 596_ IVCCC 601_ YVKIY 606_ ITVRN 611_ PQYNP 616_ GDKDT 621_ KIAKR 626_ MAVLI 631_ FTDFI 636_ CMAPI 641_ SFYAL 646_ SAILN 651_ KPLIT 656_ VSNSK 661_ ILLVL 666_ FYPLN 671_ SCANP 676_ FLYAI 681_ FTKAF 686_ QRDVF 691_ ILLSK 696_ FGICK 701_ RQAQA 706_ YRGQR 711_ VPPKN 716_ STDIQ 721_ VQKVT 726_ HDMRQ 731_ GLHNM 736_ EDVYE 741_ LIENS 746_ HLTPK 751_ KQGQI 756_SEEYM
1: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity)