High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
1_MSESS 6_ SKSSQ 11_ PLASK 16_ QEKDG 21_ TEKRG 26_ RGRPR 31_ KQPPV 36_ SPGTA 41_ LVGSQ 46_ KEPSE 51_ VPTPK 56_ RPRGR 61_ PKGSK 66_ NKGAA 71_ KTRKT 76_ TTTPG 81_ RKPRG 86_ RPKKL 91_ EKEEE 96_ EGISQ 101_ESSEE
1: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions