Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C)
1_MPSLL 6_ VLTFS 11_ PCVLL 16_ GWALL 21_ AGGTG 26_ GGGVG 31_ GGGGG 36_ AGIGG 41_ GRQER 46_ EALPP 51_ QKIEV 56_ LVLLP 61_ QDDSY 66_ LFSLT 71_ RVRPA 76_ IEYAL 81_ RSVEG 86_ NGTGR 91_ RLLPP 96_ GTRFQ 101_ VAYED 106_ SDCGN 111_ RALFS 116_ LVDRV 121_ AAARG 126_ AKPDL 131_ ILGPV 136_ CEYAA 141_ APVAR 146_ LASHW 151_ DLPML 156_ SAGAL 161_ AAGFQ 166_ HKDSE 171_ YSHLT 176_ RVAPA 181_ YAKMG 186_ EMMLA 191_ LFRHH 196_ HWSRA 201_ ALVYS 206_ DDKLE 211_ RNCYF 216_ TLEGV 221_ HEVFQ 226_ EEGLH 231_ TSIYS 236_ FDETK 241_ DLDLE 246_ DIVRN 251_ IQASE 256_ RVVIM 261_ CASSD 266_ TIRSI 271_ MLVAH 276_ RHGMT 281_ SGDYA 286_ FFNIE 291_ LFNSS 296_ SYGDG 301_ SWKRG 306_ DKHDF 311_ EAKQA 316_ YSSLQ 321_ TVTLL 326_ RTVKP 331_ EFEKF 336_ SMEVK 341_ SSVEK 346_ QGLNM 351_ EDYVN 356_ MFVEG 361_ FHDAI 366_ LLYVL 371_ ALHEV 376_ LRAGY 381_ SKKDG 386_ GKIIQ 391_ QTWNR 396_ TFEGI 401_ AGQVS 406_ IDANG 411_ DRYGD 416_ FSVIA 421_ MTDVE 426_ AGTQE 431_ VIGDY 436_ FGKEG 441_ RFEMR 446_ PNVKY 451_ PWGPL 456_ KLRID 461_ ENRIV 466_ EHTNS 471_ SPCKS 476_ SGGLE 481_ ESAVT 486_ GIVVG 491_ ALLGA 496_ GLLMA 501_ FYFFR 506_ KKYRI 511_ TIERR 516_ TQQEE 521_ SNLGK 526_ HRELR 531_ EDSIR 536_SHFSV
1: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity)