Gene name: ARF4

Uniprot entry:

P18085

Protein names:

ADP-ribosylation factor 4

Protein sequence:

1_MGLTI 6_ SSLFS 11_ RLFGK 16_ KQMRI 21_ LMVGL 26_ DAAGK 31_ TTILY 36_ KLKLG 41_ EIVTT 46_ IPTIG 51_ FNVET 56_ VEYKN 61_ ICFTV 66_ WDVGG 71_ QDRIR 76_ PLWKH 81_ YFQNT 86_ QGLIF 91_ VVDSN 96_ DRERI 101_ QEVAD 106_ ELQKM 111_ LLVDE 116_ LRDAV 121_ LLLFA 126_ NKQDL 131_ PNAMA 136_ ISEMT 141_ DKLGL 146_ QSLRN 151_ RTWYV 156_ QATCA 161_ TQGTG 166_ LYEGL 171_DWLSN

Protein annotations

Protein functions:

1: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation (PubMed:25673879)