Glutathione peroxidase 2 (GPx-2) (GSHPx-2) (EC 1.11.1.9) (Gastrointestinal glutathione peroxidase) (Glutathione peroxidase-gastrointestinal) (GPx-GI) (GSHPx-GI) (Glutathione peroxidase-related protein 2) (GPRP-2)
1_MAFIA 6_ KSFYD 11_ LSAIS 16_ LDGEK 21_ VDFNT 26_ FRGRA 31_ VLIEN 36_ VASLU 41_ GTTTR 46_ DFTQL 51_ NELQC 56_ RFPRR 61_ LVVLG 66_ FPCNQ 71_ FGHQE 76_ NCQNE 81_ EILNS 86_ LKYVR 91_ PGGGY 96_ QPTFT 101_ LVQKC 106_ EVNGQ 111_ NEHPV 116_ FAYLK 121_ DKLPY 126_ PYDDP 131_ FSLMT 136_ DPKLI 141_ IWSPV 146_ RRSDV 151_ AWNFE 156_ KFLIG 161_ PEGEP 166_ FRRYS 171_ RTFPT 176_ INIEP 181_DIKRL
1: Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis (PubMed:36608588, PubMed:8428933). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides (PubMed:36608588, PubMed:8428933). Cannot reduce phosphatidycholine hydroperoxide (PubMed:8428933)